FOR PLASTIC SURGEONS

Optimize Results.

A targeted perioperative nutritional protocol to support complex wound healing, optimise flap survival, and promote fine-line scar formation in plastic surgery.

The Clinical Challenge

Major reconstructive surgery, including free flaps and extensive tissue rearrangement, demands immense metabolic resources. The body rapidly breaks down skeletal muscle to fuel the massive regenerative response.1

3X
greater muscle protein synthesis with leucine-enriched EAAs vs intact protein.2
Zero
digestion required for free-form essential amino acids to absorb.3

Without adequate nutritional support, this catabolic state compromises microvascular circulation, delays wound healing, and increases the risk of flap necrosis or widened scars. For the patient, this translates to suboptimal aesthetic and functional outcomes.4

Supporting Regeneration

Surgical trauma induces severe anabolic resistance. Standard dietary protein is insufficient to overcome this. High-dose, leucine-enriched EAAs are required to support mTORC1 pathway activity, providing the critical substrates needed for massive tissue regeneration and flap survival.5

The Rebound Protocol

Rebound is a physician-formulated, three-phase perioperative nutrition protocol designed to optimise surgical outcomes and accelerate patient recovery in plastic surgery.

Rebound READY (Pre-op)

Attenuates surgical insulin resistance and PONV, ensuring the patient enters surgery in an optimal metabolic state, critical for microvascular perfusion.1,2

Rebound RECOVER (Post-op)

Delivers a high-leucine EAA complex to support mTORC1 signalling, providing the massive influx of anabolic substrates required for flap survival and tissue regeneration.3,4

Rebound RESTORE (Healing)

Supplies essential micronutrients (Zinc, Vitamin C, Copper) critical for robust collagen cross-linking, supporting optimal wound healing and fine-line scar formation.5

Clinical Integration

Rebound integrates into reconstructive recovery protocols. The EAA complex (Recover) provides a powerful anabolic trigger, while the Restore phase provides the biological building blocks necessary for structural integrity.6

By mitigating surgical stress and delivering precise anabolic amino acids, Rebound supports patients to heal faster and achieve superior aesthetic and functional results.

Clinical Evidence

  1. Jaxa-Kwiatkowski A, Jaxa-Kwiatkowski M, Jaxa-Kwiatkowska K, et al. Perioperative Nutritional and Metabolic Factors Affecting Surgical Outcomes in Head and Neck Cancer Free Flap Reconstruction: A Comprehensive Review. J Clin Med. 2025;14(11):3679. doi:10.3390/jcm14113679
  2. Hirsch KR, Wolfe RR, Ferrando AA. Pre- and Post-Surgical Nutrition for Preservation of Muscle Mass, Strength, and Functionality Following Orthopedic Surgery. Nutrients. 2021;13(5):1675. doi:10.3390/nu13051675
  3. Kim H, Im H, Chang H, et al. Correlation between Collagen Type I/III Ratio and Scar Formation in Patients Undergoing Immediate Reconstruction with the Round Block Technique after Breast-Conserving Surgery. Biomedicines. 2023;11(4):1089. doi:10.3390/biomedicines11041089
  4. Bruno A, D’Antimi A. Early Protein Supplementation Enhances Wound Healing and Reduces Complications Following Abdominoplasty: A Controlled Study in Non-bariatric Patients. Aesthetic Plast Surg. 2026 Mar;50(5):2145-2159. doi:10.1007/s00266-026-05626-4
  5. Vyas KS, Vasconez HC, Morrison S, et al. Fat Graft Enrichment Strategies: A Systematic Review. Plast Reconstr Surg. 2020;145(3):827-841. doi:10.1097/PRS.0000000000006557
  6. Hasiba-Pappas S, Opriessnig E, Nischwitz SP, et al. Optimizing Autologous Fat Grafting: A Systematic Review of Enhancement Strategies and Graft Survival. Aesthetic Surgery Journal. 2025;sjaf242. doi:10.1093/asj/sjaf242
READY • RECOVER • RESTORE • THRIVE