FOR SHOULDER SURGEONS

Optimize Repair.

A targeted perioperative nutritional protocol to preserve deltoid and rotator cuff volume, support tendon-to-bone healing, and accelerate rehabilitation in shoulder surgery.

The Clinical Challenge

Shoulder surgery, particularly rotator cuff repair and arthroplasty, requires a delicate balance between immobilisation for tissue healing and the prevention of rapid, profound muscle atrophy.1

14
days of sling immobilisation induces significant anabolic resistance and muscle atrophy.2
3X
greater muscle protein synthesis with leucine-enriched EAAs vs intact protein.3

This rapid degradation of the deltoid and rotator cuff musculature compromises joint stability and significantly delays the rehabilitation timeline. For the patient, this translates to a harder, longer road back to functional use of the arm.4

Combating Immobilization Atrophy

Surgical trauma and sling immobilisation induce severe anabolic resistance. Standard dietary protein is insufficient to overcome this. High-dose, leucine-enriched EAAs are required to support mTORC1 pathway activity, preserving critical muscle volume during the acute immobilisation phase.5

The Rebound Protocol

Rebound is a physician-formulated, three-phase perioperative nutrition protocol designed to optimise surgical outcomes and accelerate patient recovery in shoulder surgery.

Rebound READY (Pre-op)

Attenuates surgical insulin resistance and postoperative nausea (PONV), ensuring the patient enters surgery in an optimal metabolic state.1,2

Rebound RECOVER (Post-op)

Delivers a high-leucine EAA complex to support mTORC1 signalling, overcoming anabolic resistance to preserve deltoid and rotator cuff volume during sling immobilisation.3,4

Rebound RESTORE (Healing)

Supplies essential micronutrients (Vitamin C, Zinc, Copper) critical for robust collagen synthesis, supporting optimal tendon-to-bone healing and graft integration.5

Clinical Integration

Rebound integrates into shoulder rehabilitation protocols. The EAA complex (Recover) provides a powerful anabolic trigger, while the Restore phase provides the biological building blocks necessary for structural integrity.6

By mitigating surgical stress and delivering precise anabolic amino acids, Rebound supports patients to engage more effectively in early physical therapy, driving better functional outcomes.

Clinical Evidence

  1. Hirsch KR, Wolfe RR, Ferrando AA. Pre- and Post-Surgical Nutrition for Preservation of Muscle Mass, Strength, and Functionality Following Orthopedic Surgery. Nutrients. 2021;13(5):1675. doi:10.3390/nu13051675
  2. Brown E, Mohler SA, Kviatkovsky SA, Blake LE, Hill JR, Stambough JB, Inclan PM. Amino Acid Supplementation May Help Prevent Muscle Wasting After Orthopedic Surgery, but Additional Studies Are Warranted: A Systematic Review of Randomized Clinical Trials. HSS J. 2025;21(2):200-210. doi:10.1177/15563316241308265
  3. Dreyer HC, Owen EC, Strycker LA, et al. Essential amino acid supplementation mitigates muscle atrophy after total knee arthroplasty: a randomized, double-blind, placebo-controlled trial. JBJS Open Access. 2018;3(2):e0036. doi:10.2106/JBJS.OA.18.00036
  4. Aepala MR, Chandler AJ, Orbeta L, Confino J, Wong SE. Preoperative Nutrition in Orthopaedic Surgery. JBJS Open Access. 2025;10(4):e25.00066. doi:10.2106/JBJS.OA.25.00066
  5. Witard OC, Hughes AK, Morgan PT, et al. Protein-based perioperative nutrition interventions for improving muscle mass and functional outcomes following orthopaedic surgery. Exp Physiol. 2025;110(2):123-134. doi:10.1113/EP092237
  6. Zheng R, Huang S, Zhu J, Lin W, Xu H, Zheng X. Leucine attenuates muscle atrophy and autophagosome formation by activating PI3K/AKT/mTOR signaling pathway in rotator cuff tears. Cell Tissue Res. 2019;377(3):407-417. doi:10.1007/s00441-019-03021-x
READY • RECOVER • RESTORE • THRIVE