FOR GENERAL SURGEONS

Accelerate Recovery.

A targeted perioperative nutritional protocol to attenuate insulin resistance, support anastomotic healing, and bypass postoperative ileus in general surgery.

The Clinical Challenge

Major abdominal surgery induces profound metabolic stress, characterised by severe insulin resistance and prolonged catabolism. Early enteral feeding is often limited by postoperative ileus and gastrointestinal intolerance.1

50%
reduction in insulin sensitivity occurs following major abdominal surgery.2
Zero
digestion required for free-form essential amino acids to absorb.3

This metabolic dysfunction leads to significant lean mass loss, delayed wound healing, and increased risk of anastomotic complications. For the patient, this translates to profound weakness and a longer hospital stay.4

Bypassing Ileus

Standard whole protein requires extensive gastric digestion, which is compromised post-surgery. Rebound Recover provides free-form Essential Amino Acids (EAAs) that absorb instantly, bypassing the need for gastric digestion and allowing for early anabolic support even during transient ileus.5

The Rebound Protocol

Rebound is a physician-formulated, three-phase perioperative nutrition protocol designed to optimise surgical outcomes and accelerate patient recovery in general surgery.

Rebound READY (Pre-op)

Delivers targeted carbohydrate loading to preserve hepatic glycogen and attenuate surgical insulin resistance, a core tenet of ERAS.1,2

Rebound RECOVER (Post-op)

Provides a high-leucine EAA complex that absorbs instantly, supporting mTORC1 signalling to combat catabolism without exacerbating postoperative ileus or PONV.3,4

Rebound RESTORE (Healing)

Supplies essential micronutrients (Zinc, Vitamin C) critical for collagen synthesis, supporting robust anastomotic and incisional healing.5

Clinical Integration

Rebound integrates into abdominal ERAS protocols. The clear-liquid formulation of Ready and Recover supports compliance with early feeding guidelines while minimising gastrointestinal burden.6

By mitigating surgical stress and delivering precise anabolic amino acids, Rebound supports patients to regain strength faster, driving better functional outcomes and shorter stays.

Clinical Evidence

  1. Kiyama T, Efron DT, Tantry U, Barbul A. Effect of nutritional route on colonic anastomotic healing in the rat. J Gastrointest Surg. 1999 Jul-Aug;3(4):441-6. doi:10.1016/s1091-255x(99)80062-6.
  2. Gustafsson UO, Scott MJ, Hubner M, et al. Guidelines for perioperative care in elective colorectal surgery: Enhanced Recovery After Surgery (ERAS) Society Recommendations 2025. World J Surg. 2025;49(1):1-32. doi:10.1007/s00268-024-07777-2.
  3. Su LQ, Li Y, Wang Y, et al. Effectiveness of preoperative oral nutritional supplements in colorectal cancer surgery: a systematic review and meta-analysis. Clin Nutr. 2024;43(2):345-356. doi:10.1016/j.clnu.2023.12.008.
  4. Witard OC, Hughes AK, Morgan PT, et al. Protein-based perioperative nutrition interventions for improving muscle mass and functional outcomes following orthopaedic surgery. Exp Physiol. 2025;110(12):1802-1809. doi:10.1113/EP092237.
  5. Hirsch KR, Smith-Ryan AE, et al. Pre- and Post-Surgical Nutrition for Preservation of Muscle Mass, Strength, and Functionality Following Orthopedic Surgery. Nutrients. 2021;13(5):1675. doi:10.3390/nu13051675.
  6. Friedman J, et al. Enhanced Recovery after Surgery (ERAS) and Immunonutrition: An Evidence-Based Approach. Pract Gastroenterol. 2021;45(1):18-25.
READY • RECOVER • RESTORE • THRIVE